The human body is an amazing machine, and like all machines, they require the correct components for basic function, i.e. glucose for basic
cellular respiration. Unlike machines though, the human body tends to find a
way to work regardless of the lack of correct components, such as through gluconeogenesis.
Our
bodies have very intricate metabolic pathways that allow us to do extraordinary
things. As most people know, glucose is the main fuel source for basic metabolic
function but what happens when there is no more glucose to use. Thankfully, the
body finds a way to make glucose so that it can continue to thrive and grow. It
does this by breaking down glycogen stores first and then it begins to create
new sugars that can be used for cellular respiration. This process is known as gluconeogenesis.
Gluco being glucose neo being new and genesis being creation.
Creating “new” glucose for the purpose of cellular respiration.
This is
just one example of the intricacy that our bodies naturally possess to allow us
to grow, reproduce and be evolutionarily successful. This process shows the end
product of thousands of years of evolution that have solved the question. What
if there is not enough glucose in the environment to consume to sustain life? The
body has figured out a way to create new glucose so that in times of famine
there is still enough to go around.
The
evolution that is required for these kinds of answers takes time though. I think
that because we have so many new problems that arise so quickly then our bodies
are not able to adjust and fix the problems itself. If we slowly adapted to
eating a highly refined sugar diet then maybe our bodies would have learned to
better control the excess sugars and things like diabetes would be less of an
abundant issue. However, because we have switched to eating a more refined diet
over a generation or two, instead of a millennium or two, we are not able to adequately
deal with such a sudden shift. This is not only apparent with glucose-related
disease, but look at what is happening with the sudden shift to an over-exposure to artificial light. This has happened even faster than a generation
it has happened in as short as 20 to 30 years. We are seeing that an increase in
artificial light exposure can lead to things like sleeping disorders, mood
disorders, and a whole host of psychological problems.
We see these kinds of problems day more and
more commonly and one great explanation as to why is an increase in light
affects our sleep patterns is Ayurveda. Ayurveda is the traditional Hindu
system of medicine, which is based on the idea of balance in bodily systems. This
means that when something like light exposure is increased, it not only affects
our eyes at the moment of exposure but it will continue to affect other parts
of our body that relies on light for signals for biochemical reactions and then
on to anything that is affected by those biochemical reactions.
A great
example of these reactions getting out of hand is diabetes. Diabetes is a disease
that occurs when there is an incorrect balance of glucose in the bloodstream
and not in the cell. When this occurs over long periods of time it's common to
see problems like heart disease, stroke, kidney damage, blindness, and nerve
damage. I find it fascinating that an imbalance of glucose in the bloodstream can
cause you to lose your sight. This shows that Ayurveda is a real concern and
that our bodies have very intricate pathways that are all interconnected. It is
not that excess blood sugar attacks the eyes resulting in blindness, it’s a far
more complicated chain of events that over time affects vision and other
aspects of the body that are not directly associated with cellular respiration
or blood glucose.
But we
as humans are designed to overcome challenges like this. It is called adaptation
and evolution. If we started off slowly “learning” how to handle excess blood
sugar then over generations and several thousands of years, it is likely that
diabetes would not be a problem, similar to the way that decreased glucose in the
bloodstream is not a problem.
I think it is interesting the way you mention that many health issues and diseases have arisen because of the sudden change in the way we live. As you mentioned, evolution has not had time to allow our bodies to adjust to new diets or habits, such as the artificial light that you mention, and this has caused us issues that may not have happened before. The occurrence of type 2 diabetes in particular, which is brought on by many factors, a large portion of which is the high sugar diets. This isn't to say that if we had adjusted to this high sugar diet that evolution would have allowed us to not need medication to treat it, but it may have helped in some way.
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